SUMOylation is a transient posttranslational modification with small-ubiquitin like modifiers (SUMO1, SUMO2 and SUMO3) covalently attached to their target-proteins via a multi-step enzymatic cascade.SUMOylation modifies protein-protein interactions, enzymatic-activity or chromatin binding in Panties a multitude of key cellular processes, acting as
SPP1 facilitates cell migration and invasion by targeting COL11A1 in lung adenocarcinoma
Abstract Background Secreted phosphoprotein 1 (SPP1), an extracellular secreted glycol phosphoprotein, is closely related to tumor biologies, such as proliferation, migration, and invasion.However, the role and biological function of SPP1 in lung adenocarcinoma (LUAD) was still ambiguous.Methods SPP1 expression in LUAD tissues and its associations
CHANGES AND PERSPECTIVES OF SLOVENIAN PIG PRODUCTION BEFORE AND AFTER ACCESSION TO THE EU: THE CASE STUDY
The changes in pig production during the last six to ten years were studied in case of Farme Ihan d.d., the Slovenian pig producer.At the beginning of the period, the company produced 70 to 75 thousand slaughtering pigs per year.At the end of the period Electric Range the production increased to 150 thousand.As expected, the prices of pigs were red
Fotografia, disegno e pittura: vicinanze e lontananze. Note sulla natura della fotografia
The article focuses on the nature of the photographic medium and on the tormented relationship between photography and painting which, since their invention, have seen them as opposed, perhaps because they were structured on the assumption that both disciplines were aimed at covering the same territory: the image.One therefore wonders how much the
Successful closure of the ventricular septal defect;A rare complication after transcatheter aortic valve replacement
In this report, we present a patient Bilberry with ventricular septal defect (VSD) that was detected at follow-up one month after transcatheter aortic valve implantation (TAVI) and successfully closed percutaneously.Before the procedure, a 29 mm Portico self-expanding aortic valve prosthesis was placed in the heavy calcific aortic valve position, a